
Environmental Monitoring of Bacteria
Clive Edwards
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Volume II: Enzymology and Drugs
by Neil Osheroff, Mary-Ann Bjornsti
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Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination.
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